Category Archives: My lab

Why I, a founder of PLOS, am forsaking open access

PLEASE NOTE BEFORE YOU READ THIS THAT IT WAS WRITTEN FOR

Also posted in open access, PLoS, public access | 35 Responses

Toxoplasma, Cat Piss and Mouse Brains: my lab’s first paper on microbial manipulation of animal behavior

All animals live in a microbe rich environment, with immense numbers of bacteria, archaea, fungi and other eukaryotic microbes living in, on and around them. For some of these microbes, the association is transitory and unimportant, but many make animals their permanent home, or interact with them in ways that are vital for their survival. Many […]

Also posted in EisenLab preprints, microbial manipulation of animal behavior | 17 Responses

Please review our new paper: Sequencing mRNA from cryo-sliced Drosophila embryos to determine genome-wide spatial patterns of gene expression

It’s no secret to people who read this blog that I hate the way scientific publishing works today. Most of my efforts in this domain have focused on removing barriers to the access and reuse of published papers. But there are other things that are broken with the way scientists communicate with each other, and […]

Also posted in EisenLab, gene regulation, open access, science | 24 Responses

Zelda (the coolest transcription factor ever) is a master regulator of embryonic adolescence

PLoS Genetics just published a paper from my lab describing our analysis of the binding and activity of a remarkable protein, known as Zelda, that appears to be a master regulator of genome activation in the earliest stages of Drosophila development, and thereby plays a major role in shaping the form and function of the mature […]

Also posted in cool science, evolution, gene regulation, genetics, science | 2 Responses

Nature: Big is beautiful

Nature has a brief “Research Highlight” on our recent PLoS One paper. Nature 458, 263 (19 March 2009) | doi:10.1038/458263a; Published online 18 March 2009 Genomics: Big is beautiful PLoS ONE 4, e4688 (2009) Finding gene regulators in the fruitfly Drosophila melanogaster has proved difficult: looking for conserved non-coding DNA sequences, a method that works well in vertebrates, has been […]

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